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John Brockman is a literary agent (and agent for my book, Net Attitude) and the publisher of Edge.org, a Web site devoted to science. At the end of each year, John poses a question to leading scientists, writers and futurists. In 2002, he asked respondents to imagine that they had been nominated as White House science adviser and that President Bush had sought their answer to “What are the pressing scientific issues for the nation and the world, and what is your advice on how I can begin to deal with them?” The New York Times published the very interesting collection of responses.